Ultra-thin rigid endoscope: two-photon imaging through a graded-index multi-mode fiber.
نویسندگان
چکیده
Rigid endoscopes like graded-index (GRIN) lenses are known tools in biological imaging, but it is conceptually difficult to miniaturize them. In this letter, we demonstrate an ultra-thin rigid endoscope with a diameter of only 125 μm. In addition, we identify a domain where two-photon endoscopic imaging with fs-pulse excitation is possible. We validate the ultra-thin rigid endoscope consisting of a few cm of graded-index multi-mode fiber by using it to acquire optically sectioned two-photon fluorescence endoscopic images of three-dimensional samples.
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ورودعنوان ژورنال:
- Optics express
دوره 24 2 شماره
صفحات -
تاریخ انتشار 2016